Technical Specialist - Single Cell & Spatial Biology
Department: Research Platforms Office
About us
King’s Smart Trials Hub (STH) is a globally distinctive multi-omics centre, located at Guy’s Hospital campus within Research Infrastructure, part of Research Management and Innovation Directorate at King’s College London.
The Hub brings together state-of-the-art spatial and non-spatial ‘omics’ technologies to enable full molecular profiling of cells, tissues and liquid biopsies and leverages advanced, multi-modal technologies to investigate disease biology at high resolution, supporting the equitable development of personalised therapies.
About the role
As Technical Specialist in Single Cell Spatial Transcriptomics and Spatial Proteomics, you’ll play a key role in delivering and advancing cutting-edge single-cell and spatial omics technologies and workflows within the Smart Trials Hub.
Working as part of a highly collaborative and multidisciplinary team, the role provides expert technical support across a broad range of academic and commercial research projects, applying specialist knowledge of single-cell spatial transcriptomics and spatial proteomics, and associated technologies.
The role is responsible for delivering and optimising advanced single-cell and spatial omics workflows, including RNA & protein antibody barcoding protocols, cell sorting, next-generation sequencing (NGS), whole transcriptome analysis, method development, data acquisition and quality control. You’ll ensure the generation of high-quality, reproducible datasets and contribute to the continuous development of the facility’s research capabilities.
You’ll provide specialist advice on experimental design and emerging methodologies, maintain equipment and workflows to a high standard, troubleshoot complex technical issues, and ensure the highest levels of sample and data integrity. The role requires meticulous attention to detail, accurate record keeping and a commitment to delivering high-quality research outcomes.
This is a full-time post (35 hours per week), and you will be offered an indefinite contract. This is an onsite, facility-based role and the post holder is expected to be on campus for the full working week.
About you
To be successful in this role, we are looking for candidates to have the following skills and experience:
Essential criteria
- PhD in relevant subject area, or equivalent experience gained in a research setting.
- Demonstrable hands-on experience with spatial transcriptomics and/or tissue profiling techniques, such as Chromium, Visium, Xenium platforms.
- Experience with data analysis and quality control of single cell sequencing and spatial transcriptomic data.
- Experience in method development and optimising workflows to deliver robust, reproducible and high-quality scientific data across a range of sample types.
- Experience in the operation, maintenance and troubleshooting of equipment.
- Experience working effectively within multidisciplinary teams, building collaborative relationships with colleagues, researchers and stakeholders. Demonstrable ability to communicate openly, share knowledge, support others, and contribute to a positive working environment.
- Excellent communication, written and verbal, with the ability to communicate complex scientific and technical information clearly and effectively to a range of audiences, including through reports, publications and presentations.
- Demonstrable ability to work independently, prioritise competing demands, and manage multiple projects or activities simultaneously while meeting deadlines.
Desirable criteria
- Experience working with human tissue and clinical data with an awareness of relevant governance and data protection considerations.
- Experience with data analysis software such as 10x Genomics Ranger platforms for re-analysis and deeper data interpretation.
- Experience working in a research facility environment.
- Experience of delivering technical training or hands-on support to researchers or colleagues.
Downloading a copy of our Job Description
Full details of the role and the skills, knowledge and experience required can be found in the Job Description document, provided at the bottom of the page. This document will provide information of what criteria will be assessed at each stage of the recruitment process.
Further Information
At King’s, we believe that the diversity of our community and a culture that is welcoming, open, inclusive and collaborative, are great strengths of the university.
The Equality Act of 2010 protects the rights of our students and staff and provides a framework to fulfil our duties to eliminate unlawful discrimination, harassment and victimisation and in addition, to advance equality of opportunity and foster good relations between those who share a protected characteristic and those who do not. At times, this will include balancing rights and beliefs that can feel in tension.
We are committed to free speech and to academic freedom, believing that our foundational purpose as a university, is to create spaces where a wide range of ideas, including ideas that are controversial, can be discussed and debated, and where members of our community can express lawful views without fear of intimidation, harassment or discrimination.
When engaging in the robust exchange of ideas, we ask that our community is mindful of our Dignity at King’s guidance.
We ask all candidates to submit a copy of their CV, and a supporting statement, detailing how they meet the essential criteria listed in the person specification section of the job description. If we receive a strong field of candidates, we may use the desirable criteria to choose our final shortlist, so please include your evidence against these where possible.
We reserve the right to close adverts early due to the volume of applications we receive. While the closing date may change, all adverts will close at 23:59 to allow sufficient time for applications to be submitted on that day.
We encourage you to apply at the earliest opportunity to avoid disappointment as once we have closed a vacancy you will be unable to submit your application.
To find out how our managers will review your application, please take a look at our ‘How we Recruit’ pages.
Grade and Salary: £45,031 - £52,514 per annum, including London Weighting Allowance
Job ID: 160125
Post Date: 02-Oct-2026
Close Date: 08-Nov-2026
Contact Person: Steven Lynham
Contact Details: Steven.lynham@kcl.ac.uk
