About us
King’s Smart Trials Hub (STH) is a globally distinctive multi-omics centre, located at Guy’s Hospital campus within Research Infrastructure, part of Research Management and Innovation Directorate at King’s College London.
The Hub brings together state-of-the-art spatial and non-spatial ‘omics’ technologies to enable full molecular profiling of cells, tissues and liquid biopsies and leverages advanced, multi-modal technologies to investigate disease biology at high resolution, supporting the equitable development of personalised therapies.
About the role
The Senior Computational Biologist is part of a highly collaborative and inclusive team. The role leads on developing and optimising analysis pipelines and integration for multi-omic data generated from bulk and spatial transcriptomics and proteomics, as well as spatial metabolomic, lipidomic, peptide/protein and metallomic mass spectrometry.
The role requires a strong background in statistical methods and machine-learning tools with experience of programming (such as Python) being desirable.
Reporting to the Smart Trials Hub Manager, you will work closely with a multidisciplinary team to deliver a high-quality research service to both academic and commercial customers.
This is a full-time post (35 hours per week), and you will be offered an indefinite contract. This is an onsite, facility-based role and the post holder is expected to be on campus for the full working week.
About you
To be successful in this role, we are looking for candidates to have the following skills and experience:
Essential criteria
- PhD in relevant subject area, or equivalent experience gained in a research setting
- Significant post-doctoral experience or equivalent industry experience (typically three years or more) in omics analysis, including spatial omics
- Strong programming skills, with experience using Python or relevant programming language for data analysis
- Expertise in multi-omics data integration and statistical modelling, applied to complex biological datasets
- Experience working with high-performance computing (HPC) environments
- Experience of working to quality assurance and quality control standards within a laboratory or research environment, ensuring data integrity and reproducibility across workflows
- Excellent written and verbal communication skills with the ability to present complex analytical concepts clearly to a range of audiences, including through reports, publications and presentations.
- Experience working collaboratively in multidisciplinary teams and at the interface between biological data, biologists and data scientists/software engineers
Desirable criteria
- Practical experience using machine-learning tools and frameworks for biological or biomedical data analysis
- Experience working with human tissue and clinical data, including an understanding of relevant governance or data protection considerations
- Experience developing computational tools or workflows to support data management, analysis and reproducibility
- Experience of delivering technical training or hands-on support to researchers or colleagues
Downloading a copy of our Job Description
Full details of the role and the skills, knowledge and experience required can be found in the Job Description document, provided at the bottom of the page. This document will provide information of what criteria will be assessed at each stage of the recruitment process.
Further Information
At King’s, we believe that the diversity of our community and a culture that is welcoming, open, inclusive and collaborative, are great strengths of the university.
The Equality Act of 2010 protects the rights of our students and staff and provides a framework to fulfil our duties to eliminate unlawful discrimination, harassment and victimisation and in addition, to advance equality of opportunity and foster good relations between those who share a protected characteristic and those who do not. At times, this will include balancing rights and beliefs that can feel in tension.
We are committed to free speech and to academic freedom, believing that our foundational purpose as a university, is to create spaces where a wide range of ideas, including ideas that are controversial, can be discussed and debated, and where members of our community can express lawful views without fear of intimidation, harassment or discrimination.
When engaging in the robust exchange of ideas, we ask that our community is mindful of our Dignity at King’s guidance.
We ask all candidates to submit a copy of their CV, and a supporting statement, detailing how they meet the essential criteria listed in the person specification section of the job description. If we receive a strong field of candidates, we may use the desirable criteria to choose our final shortlist, so please include your evidence against these where possible.
We reserve the right to close adverts early due to the volume of applications we receive. While the closing date may change, all adverts will close at 23:59 to allow sufficient time for applications to be submitted on that day.
We encourage you to apply at the earliest opportunity to avoid disappointment as once we have closed a vacancy you will be unable to submit your application.
To find out how our managers will review your application, please take a look at our ‘How we Recruit’ pages.
Grade and Salary: £53,947 - £63,350 per annum, including London Weighting Allowance
Job ID: 160465
Post Date: 06-Oct-2026
Close Date: 08-Nov-2026
Contact Person: Steven Lynham
Contact Details: Steven.lynham@kcl.ac.uk
