Senior Scientific Officer - Dr. Riccardo Mezzadra
Dissecting the Interplay Between Senescence and Antitumor Immunity in Liver Cancer
Salary: From £29,761 to £47,625 based on qualification and experience.
Contract term : Permanent
About us
The CRUK Scotland Institute is a cancer research institute, situated in Glasgow with approximately 250 researchers split across 30 research groups consisting of PIs, postdoctoral scientists, PhD students and scientific officers. It is one of Europe's leading cancer research centres, supporting cutting-edge work into the molecular mechanisms of cancer development. As well as core support from Cancer Research UK, the Institute also receives an additional third of its total income from external grants and industry collaborations. It has an excellent reputation for fundamental cancer research, including world-class metabolism studies and renowned in vivo modelling of tumour growth and metastasis.
Project Outline
Join the newly established laboratory of Dr Riccardo Mezzadra, launching in March 2027 and funded through a CRUK Career Development Fellowship. Dr Mezzadra's research focuses on understanding how conventional cancer therapies reshape anti-tumour immune responses, with particular expertise in T cell immunology, tumour-immune interactions, and in vivo models of cancer.
This is a unique opportunity to become an early member of a new research group investigating how conventional cancer therapies influence anti-tumour immunity and responses to immunotherapy. Working closely with the Group Leader and other members of the laboratory, you will play a central role in generating and analysing data from in vivo studies, cell culture and molecular biology experiments, while helping to establish the laboratory's protocols, systems and ways of working from the outset.
Key Responsibilities
- Conduct and support in vivo and in vitro experiments using mouse models of cancer and mouse and human cell lines.
- Generate, collect and analyse experimental data using a range of cellular and molecular biology techniques.
- Play a key role in establishing new laboratory protocols, experimental workflows, reagents and model systems.
- Support the day-to-day operation of the laboratory, including management of stocks, inventories and shared resources.
- Collaborate effectively with colleagues across the Institute and contribute to a positive and productive research environment.
- Contribute to the delivery of the laboratory's research objectives and the dissemination of research findings.
About You
Essential
- Bachelor's or Master's degree in biomedical sciences, cell biology, immunology, or a related discipline.
- Experience of laboratory-based experimental research.
- Good working knowledge of molecular biology techniques.
- Strong organisational, communication and teamwork skills.
- Ability to work independently while contributing effectively within a multidisciplinary research team.
Desirable
- Experience of tissue culture, flow cytometry, cancer biology, animal research, or molecular biology techniques.
- Experience working with mouse models of cancer.
- Previous laboratory management or laboratory organisation experience.
For informal enquiries, please email Dr Riccardo Mezzadra at Riccardo.mezzadra@glasgow.ac.uk
Equity, Diversity and Inclusion
Our vision is to build and maintain a diverse and inclusive research culture based on our shared values of Innovate, Respect, Integrity, Teamwork and Excellence. These values, which underpin our behaviours and everything we do, allow all our people to realise their full potential. The diversity of our staff and students is also what makes the Institute such a vibrant place to work and advance discoveries in cancer research. Family friendly policies, our collaborative ethos, a focus on good mental health and well-being and opportunities for all help to create an enjoyable and inclusive workplace where your voice matters.
Employee Benefits
- Competitive salary
- 40.5 days annual leave including bank holidays (FTE)
- Defined contribution pension scheme
- Free life assurance scheme
- Employee Assistance Programme
- Interest free season ticket loans
- Additional maternity pay for 6 months at full salary
- Shared parental leave including up to 6 weeks paid at full salary
- Cycle to work scheme saving tax and NI on cycle purchase and spreading repayments over up to 12 months
- Access to employee benefit schemes with discounts on supermarkets, cinema, travel and much more.
- On-site secure parking
All applications must be made via our website:
https://www.crukscotlandinstitute.ac.uk/careers/current-vacancies/
Closing date for applications: 4th December 2026
