{"job":{"jobId":1212406,"fk_accountId":null,"fk_organizationId":463,"fk_adminAccountId":null,"title":"Postdoctoral Associate, Synthetic Biology Center","description":"\n\n<p><strong>Working at MIT offers opportunities, an environment, a culture – and benefits – that just aren’t found together anywhere else. If you’re curious, motivated, want to be part of a unique community, and help shape the future – then take a look at this opportunity.</strong></p>\n\n\n<p><strong>POSTDOCTORAL ASSOCIATE</strong>, <em>Biological Engineering (BE)-Synthetic Biology Center</em>, to work on a research project at the intersection of cell fate reprograming, mammalian synthetic biology, and feedback control. Will join the labs of Jim Collins (http://synbio.mit.edu/) and Ron Weiss (http://groups.csail.mit.edu/synbio/) and a team including Domitilla Del Vecchio (https://scripts.mit.edu/~ddv/index.php) and Thorsten Schlaeger (http://stemcell.childrenshospital.org/about-us/leadership-faculty-staff/thorsten-m-schlaeger/). The project seeks to develop a new and general approach to cell fate reprogramming based on the design of synthetic genetic feedback control circuits in mammalian cells.</p>\n\n\n<p>These circuits will have unprecedented ability to accurately control endogenous transcription factors’ concentration in the face of noise and endogenous gene regulatory network dynamics. As a first application, induced pluripotent stem cell (iPSC) reprogramming will be considered with an aim of improving currently low efficiency, kinetics of reprogramming, and quality of produced cells. It will then consider other cell fate conversion and directed differentiation tasks. Responsibilities include virus production and titration, infection, lineage tracing, next-generation sequencing, bioinformatics analysis, flow cytometry, live imaging, antibody staining, qRT-PCR, mammalian and stem cell culture, iPSC reprogramming of human somatic cells, maintaining partially and fully reprogrammed human iPSCs, in vitro differentiation assays; cooperating with a student with a modeling/quantitative background and a postdoctoral with a synthetic biology background; and presenting to the scientific community through talks and publications. </p>\n\n\n<p><strong>Job Requirements</strong></p>\n\n\n<p><strong><em>REQUIRED</em>:</strong> Ph.D. in biological sciences, engineering, or related field; experience in mammalian cell culture, stem cells, and next-generation sequencing; biological experience in cell biology; self-motivation; ability to prioritize and multitask in a dynamic, multidisciplinary, team-oriented setting; strong analytical, problem-solving, documentation, organizational, and interpersonal skills; and ability to execute detailed technical protocols meticulously. Developmental biology expertise and flow cytometry skills would be ideal. <strong>Job #16934</strong></p>\n\n\n<p>In addition to applying online with a cover letter and CV via the MIT website, please submit the following to ddv@mit.edu as a single pdf document:</p>\n\n\n<ol>\n<li>a cover letter specifying relevant qualifications and training,</li>\n<li>curriculum vitae,</li>\n<li>statement of current research interests and expertise (two page maximum),</li>\n<li>two letters of reference, and</li>\n<li>one peer-reviewed publication. Please include “Application for Postdoc-mammalian genetic engineering” in the email subject line. Applications will be reviewed on a rolling basis.</li>\n</ol>\n\n\n<p>A minimum one year commitment is required. </p>\n\n\n<p>Employment is contingent upon the successful completion of a background check.</p>\n\n\n<p>MIT is an equal employment opportunity employer. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of race, color, sex, sexual orientation, gender identity, religion, disability, age, genetic information, veteran status, ancestry, or national or ethnic origin.</p>\n\n\n<p>MIT considers equivalent combinations of experience and education for certain jobs. All candidates who believe they possess equivalent experience and education are encouraged to apply.</p>\n\n\n<p>MIT considers equivalent combinations of experience and education for certain jobs. All candidates who believe they possess equivalent experience and education are encouraged to apply.</p>\n\n\n","pdfUrl1":null,"location":"Massachusetts, United States","location1":"북아메리카","location2":null,"location3":null,"type":"2","applyUrl":"https://careers.peopleclick.com/careerscp/client_mit/external/jobDetails/jobDetail.html?jobPostId=14661&localeCode=en-us","fileUrl1":null,"fileUrl2":null,"fileUrl3":null,"fileUrl4":null,"fileUrl5":null,"fileUrl6":null,"fileUrl7":null,"workingHour":"Full Time","contractType":"Fixed Term","salary":null,"original_id":"UNI|224826","original_domain":"https://www.timeshighereducation.com/unijobs","original_url":"https://www.timeshighereducation.com/unijobs/listing/224826/postdoctoral-associate-synthetic-biology-center/","original_isPremium":"false","closeType":2,"closedAt":null,"requireEducation":0,"managerTel":"","managerFax":null,"managerEmail":null,"managerName":"MIT MASSACHUSETTS INSTITUTE OF TECHNOLOGY","managerPhone":null,"managerAddress":null,"log_hit":3,"log_like":0,"publishState":1,"organizationName":null,"organizationName_en":null,"organizationName_alt":null,"createdAt":"2020-09-09T00:00:00.000Z","updatedAt":"2020-09-18T13:19:51.000Z"},"organization":{"organizationId":463,"lv1Id":null,"lv2Id":null,"name":"Massachusetts Institute of Technology(MIT)","name_en":"Wentworth Institute of Technology","name_alt":",Massachusetts Institute of Technology,MIT,MIT MASSACHUSETTS INSTITUTE OF TECHNOLOGY,","introduction":"<p>The Massachusetts Institute of Technology (MIT) is an independent, coeducational, private research university based in the city of Cambridge, Massachusetts.</p><p> </p><p>Established in 1861, MIT aims to ‘further knowledge and prepare students in science, technology and other fields of study that will best benefit the nation and the world today’. Its motto is Mens et Manus, which translates as “Mind and Hand”.</p><p>The university lays claim to 85 Nobel Laureates, 58 National Medal of Science winners, 29 National Medal of Technology and Innovation winners and 45 MacArthur Fellows. Among its impressive alumni is Kofi Annan, former secretary-general of the United Nations.</p><p>Scientific discoveries and technological advances accredited to MIT include the first chemical synthesis of penicillin, the development of radar, the discovery of quarks, and the invention of magnetic core memory, which enabled the development of digital computers.</p><p>MIT is currently organised into five different schools: architecture and planning, engineering, humanities, arts and social sciences, management and science.</p><p> </p><p>It is home to around 1,000 faculty members and over 11,000 undergraduate and graduate students. MIT’s current areas of research include digital learning, sustainable energy, Big Data, human health and much more.</p><p>In addition to its emphasis on innovation and entrepreneurship, MIT also boasts a diverse and vibrant campus environment with a wide array of student groups. The campus is arranged over 168 acres within Cambridge, and features 18 student residences, 26 acres of playing fields, 20 gardens and green-space areas, as well as over 100 public works of art.</p><p> </p><p>MIT estimates that all its living alumni have between them launched more than 30,000 active companies, created 4.6 million jobs and generated roughly $1.9 trillion in annual revenue.</p><p>Taken together, this ‘MIT Nation’ is equivalent, they say, to the 10th-largest economy in the world.</p>","logoImg":"","logoImgSquare":"https://s3.ap-northeast-2.amazonaws.com/jobs.ac.kr/dev/images/sdlkjuflksj_106114423102.jpg","homepageUrl":"http://web.mit.edu/","infoUrl":"https://www.timeshighereducation.com/world-university-rankings/massachusetts-institute-technology","country":"US","state":"Cambridge","location":"북아메리카","address":"77 Massachusetts Avenue, Cambridge, Massachusetts, 02139-4307, United States","phoneNumber":"+1 617-253-1000","faxNumber":"","type":1,"univType1":"대학","univType2":"대학교","univType3":"","univType4":"본교","establishedAt":"1861-04-10T00:00:00.000Z","count_majors":null,"count_students":null,"meta_competitiveness":"","publishState":1,"updatedAt":"2020-04-03T18:30:02.000Z","createdAt":"2020-03-04T20:13:07.000Z","default_1_bannerImage":null,"default_1_bannerImageMobile":null,"default_2_bannerImage":null,"default_2_bannerImageMobile":null,"default_3_bannerImage":null,"default_3_bannerImageMobile":null}}