{"job":{"jobId":1309736,"fk_accountId":null,"fk_organizationId":465,"fk_adminAccountId":null,"title":"Postdoctoral position in mitochondrial metabolism and transport","description":"\n\n<p><strong>Postdoctoral position in mitochondrial metabolism and transport</strong></p>\n\n\n<p><strong>School </strong>Harvard T.H. Chan School of Public Health</p>\n\n\n<p><strong>Department/Area </strong></p>\n\n\n<p><strong>Position Description </strong>\nA postdoctoral position is available in the Kory lab in the Department of Molecular Metabolism at the Harvard T.H. Chan School of Public Health.\nWe are looking for highly motivated individuals to join our efforts in studying mitochondrial metabolism and transport in mammals. The strong focus on metabolism research in the Department and the general excellence of biomedical research in the area provide an ideal environment for postdoctoral training in metabolism, cell biology and metabolic diseases, including cancer. https://www.hsph.harvard.edu/molecular-metabolism/</p>\n\n\n<p>Research in the Kory lab focuses on the role of organelles in metabolic compartmentalization and regulation. Our current work centers on mitochondria, critical organelles in metabolism generating both energy and precursors for biosynthesis. Beyond their metabolic roles, mitochondria are being recognized as important signaling hubs and mitochondrial dysfunction has been associated with major diseases including cancer, diabetes, and neurodegeneration. For mitochondria to function properly metabolites must be efficiently exchanged with the rest of the cell in a regulated manner. While metabolites can diffuse through pores in the outer membrane, the inner mitochondrial membrane is impermeable to most metabolites and separates two chemically contrasting environments.</p>\n\n\n<p>The Kory lab takes multi-faceted approaches including functional genomics, metabolite profiling, cell biology, biochemistry and imaging to understand how mitochondria achieve efficient metabolite exchange and conversion while maintaining the unique chemical environment of the mitochondrial matrix. Our goal is to use mitochondrial transporter proteins as tools to interrogate metabolic and signaling pathways to understand how mitochondria perform their roles in maintaining metabolic homeostasis. Ultimately, we hope our research will contribute to progress in the treatment of diseases with deregulated metabolism such as cancer.</p>\n\n\n<p><strong>Current projects address</strong></p>\n\n\n<ul>\n<li>how mitochondrial metabolite flux is adjusted to proliferative demand and cell function</li>\n<li>how metabolic processes inside mitochondria, such as TCA cycle, electron transport chain and one-carbon metabolism are coordinated with cytosolic metabolism</li>\n<li>what the roles of mitochondrial metabolites are in metabolic signaling, communication and regulation of physiology</li>\n</ul>\n\n\n<p>We are building a supportive training and mentoring environment to answer these questions at the molecular and physiological level.</p>\n\n\n<p>Kory Lab Website: <a data-mz=\"\" href=\"https://www.kory-lab.com\" rel=\"no-follow\">www.kory-lab.com</a></p>\n\n\n<p>The Harvard T.H. Chan School of Public Health seeks to recruit, develop, promote, and retain the world’s best scholars. We are committed to upholding the values of diversity, equity, and inclusion in our hiring and promotion processes. Women and individuals from underrepresented racial and ethnic minority groups are strongly encouraged to apply.</p>\n\n\n<p>Harvard University seeks to find, develop, promote, and retain the world’s best scholars. Harvard is an Affirmative Action/Equal Opportunity Employer. Applications from women and minority candidates are strongly encouraged.</p>\n\n\n<p>Information on resources for career development and work/life balance at HSPH can be found at: <a data-mz=\"\" href=\"http://hsph.me/resources-career-development-and-work-life-balance\" rel=\"no-follow\">http://hsph.me/resources-career-development-and-work-life-balance</a></p>\n\n\n<p><strong>Basic Qualifications </strong></p>\n\n\n<ul>\n<li>Ph.D. in biological sciences, biophysics, biochemistry, or related filed</li>\n<li>Motivation to understand metabolism, normal biology and disease at a mechanistic level</li>\n<li>Excellent communication, writing, and organizational skills</li>\n</ul>\n\n\n<p><strong>Additional Qualifications </strong> </p>\n\n\n<ul>\n<li>Biochemistry/Structural Biology</li>\n<li>Metabolomics, mass spectrometry</li>\n<li>Animal experiments (e.g., genetic, surgical)</li>\n<li>Microscopy</li>\n</ul>\n\n\n<p><strong>Special Instructions </strong> \nPlease email application materials including:</p>\n\n\n<p>CV and contact information for 2-3 references to Dr. Nora Kory- <a data-mz=\"\" href=\"mailto:nkory@wi.mit.edu\" rel=\"no-follow\">nkory@wi.mit.edu</a></p>\n\n\n<p><strong>Contact Information </strong>\nDr. Nora Kory</p>\n\n\n<p>Contact Email <a data-mz=\"\" href=\"mailto:nkory@wi.mit.edu\" rel=\"no-follow\">nkory@wi.mit.edu</a></p>\n\n\n<p><strong>Equal Opportunity Employer </strong>\nWe are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, gender identity, sexual orientation, pregnancy and pregnancy-related conditions or any other characteristic protected by law. </p>\n\n\n","pdfUrl1":null,"location":"Cambridge, Massachusetts (US)","location1":"북아메리카","location2":null,"location3":null,"type":"2","applyUrl":"https://academicpositions.harvard.edu/postings/9802","fileUrl1":null,"fileUrl2":null,"fileUrl3":null,"fileUrl4":null,"fileUrl5":null,"fileUrl6":null,"fileUrl7":null,"workingHour":"Full Time","contractType":"Fixed Term","salary":null,"original_id":"UNI|228394","original_domain":"https://www.timeshighereducation.com/unijobs","original_url":"https://www.timeshighereducation.com/unijobs/listing/228394/postdoctoral-position-in-mitochondrial-metabolism-and-transport-/?LinkSource=PremiumListing","original_isPremium":"true","closeType":2,"closedAt":null,"requireEducation":0,"managerTel":"","managerFax":null,"managerEmail":"nkory@wi.mit.edu","managerName":"HARVARD UNIVERSITY","managerPhone":null,"managerAddress":null,"log_hit":6,"log_like":0,"publishState":1,"organizationName":null,"organizationName_en":null,"organizationName_alt":null,"createdAt":"2020-10-06T00:00:00.000Z","updatedAt":"2020-10-07T10:06:55.000Z"},"organization":{"organizationId":465,"lv1Id":null,"lv2Id":null,"name":"Harvard University","name_en":"Harvard University","name_alt":null,"introduction":"<p>Dating back to 1636, Harvard University is the oldest university in the US and is regarded as one of the most prestigious in the world.</p><p> </p><p>It was named after its first benefactor, John Harvard, who left his library and half his estate to the institution when he died in 1638.</p><p> </p><p>The private Ivy League institution has connections to more than 45 Nobel laureates, over 30 heads of state and 48 Pulitzer prizewinners. It has more than 323,000 living alumni, including over 271,000 in the US and nearly 52,000 in 201 other countries. Thirteen US presidents have honorary degrees from the institution; the most recent of these was awarded to John F. Kennedy in 1956.</p><p> </p><p>Faculty members who have been awarded a Nobel prize in recent years include chemist Martin Karplus and economist Alvin Roth, while notable alumni who were given the honour include former US vice-president Al Gore, who won the Peace Prize in 2007, and poet Seamus Heaney, who was a professor at Harvard from 1981 to 1997.</p><p> </p><p>Situated in Cambridge, Massachusetts, Harvard’s 5,000-acre campus houses 12 degree-granting schools in addition to the Radcliffe Institute for Advanced Study, two theatres and five museums. It is also home to the largest academic library in the world, with 20.4 million volumes, 180,000 serial titles, an estimated 400 million manuscript items, 10 million photographs, 124 million archived web pages and 5.4 terabytes of born-digital archives and manuscripts.</p><p> </p><p>There are more than 400 student organisations on campus, and Harvard’s medical school is connected to 10 hospitals.</p><p> </p><p>The university receives one of the largest financial endowments of any higher education institution in the world; it created $1.5 billion in the fiscal year ended June 2013 – more than a third of Harvard’s total operating revenue in that year.</p><p> </p><p>Harvard’s official colour is crimson, following a vote in 1910, after two student rowers provided crimson scarves to their teammates so that spectators could differentiate the university’s team during a regatta in 1858.</p>","logoImg":"","logoImgSquare":"https://s3.ap-northeast-2.amazonaws.com/jobs.ac.kr/dev/images/다운로드 (22)_1244644744420.png","homepageUrl":"https://www.harvard.edu/","infoUrl":"https://www.timeshighereducation.com/world-university-rankings/harvard-university","country":"US","state":"","location":"북아메리카","address":"Massachusetts Hall, Cambridge, Massachusetts, 02138, United States","phoneNumber":"","faxNumber":"","type":1,"univType1":"대학","univType2":"대학교","univType3":"","univType4":"본교","establishedAt":"1636-11-29T00:00:00.000Z","count_majors":null,"count_students":null,"meta_competitiveness":"","publishState":1,"updatedAt":"2020-03-09T15:50:13.000Z","createdAt":"2020-03-04T20:13:07.000Z","default_1_bannerImage":null,"default_1_bannerImageMobile":null,"default_2_bannerImage":null,"default_2_bannerImageMobile":null,"default_3_bannerImage":null,"default_3_bannerImageMobile":null}}