{"job":{"jobId":2423098,"fk_accountId":null,"fk_organizationId":494,"fk_adminAccountId":null,"title":"Research Associate","description":"\n\n<p style=\"margin-bottom: 20px; font-family: san-serif;\"><strong>Job description</strong></p>\n\n\n<p style=\"margin-bottom: 20px; font-family: san-serif;\">The Laboratory of Dr Graeme Hewitt is a newly formed research group at Kings College London School of Cancer & Pharmaceutical Sciences. Our group uses genetic screens and a range of molecular and cell biology techniques to elucidate the molecular mechanisms of DNA damage repair. With a specific focus on understanding how the DDR can be targeted alongside radiotherapy to improve therapy response and overcome resistance.</p>\n\n\n<p style=\"margin-bottom: 20px; font-family: san-serif;\">We seek a talented postdoc who will work as part of a multidisciplinary team to investigate novel approaches to targeting the DNA Damage Response (DDR) in Cancer therapy.</p>\n\n\n<p style=\"margin-bottom: 20px; font-family: san-serif;\">This project will employ whole genome CRISPR Cas9 screens to uncover novel vulnerabilities and resistance mechanisms in response to different modalities of radiation therapy. Hits will be validated and investigated further to gain a detailed molecular understanding of mechanisms of therapy resistance and radio sensitisation.</p>\n\n\n<p style=\"margin-bottom: 20px; font-family: san-serif;\">Your research will take place in the Hewitt lab at Kings College London School of Cancer and Pharmaceutical Sciences. As part of the City of London RadNet network between Kings, UCL, Barts and the Francis Crick institute you will have access to an extensive network of knowledge and state of the art technologies.</p>\n\n\n<p style=\"margin-bottom: 20px; font-family: san-serif;\">Hewitt lab has ongoing collaborations with partners in industry, allowing lab members the valuable opportunity to gain insight into drug discovery and development processes.</p>\n\n\n<p style=\"margin-bottom: 20px; font-family: san-serif;\">\nThis post will be offered on an a fixed-term contract for 3 years, with a possibility of extension. \nThis is a full-time post - 100% full time equivalent</p>\n\n\n<p style=\"margin-bottom: 20px; font-family: san-serif;\"><strong>Key responsibilities</strong></p>\n\n\n<ul>\n<li>Conduct a novel research project as part of multidisciplinary research team. </li>\n<li>Develop new techniques and reagents to address research questions in the DDR/oncology field. </li>\n<li>Present research findings at seminars, journal clubs and national/international conferences. </li>\n<li>Maintain accurate and up to date lab records. </li>\n<li>Share skills by training others and a willingness to work collaboratively. </li>\n<li>Contribute to the scientific literature through the writing of papers and review articles. </li>\n</ul>\n\n\n<p style=\"margin-bottom: 20px; font-family: san-serif;\">The above list of responsibilities may not be exhaustive, and the post holder will be required to undertake such tasks and responsibilities as may reasonably be expected within the scope and grading of the post. \n \n<strong>Skills, knowledge, and experience <br/>\n <br/>\nEssential criteria </strong>\n \n1. PhD in molecular and cell biology. \n2. Proven ability to independently design and execute experiments. \n3. Highly skilled in data analysis and interpretation. \n4. Strong scientific track-record of published/accepted papers in reputable peer-reviewed journals. \n5. Strong Interpersonal, organizational and communication skills. \n6. Ability to work collaboratively in a multidisciplinary team. \n \n<strong>Desirable criteria</strong>\n \n1. Experience working in genome stability or DDR related field. \n2. Experience in a range of cell biology and in vitro biochemical skills that can be applied to oncology research. E.g. CRISPR Cas9 gene editing, flow cytometry, fixed and live-cell fluorescent microscopy and survival assays. \n3. Experience in analysing and interpreting large “omics” data sets. \n \n \n* Please note that this is a PhD level role but candidates who have submitted their thesis and are awaiting award of their PhDs will be considered. In these circumstances the appointment will be made at Grade 5, spine point 30 with the title of Research Assistant. Upon confirmation of the award of the PhD, the job title will become Research Associate and the salary will increase to Grade 6. \n \n<strong>Further information</strong>\n \nThis post is subject to Disclosure and Barring Service and Occupational Health clearance. </p>\n\n\n","pdfUrl1":null,"location":"London (Greater)","location1":"유럽","location2":null,"location3":null,"type":"2","applyUrl":"https://jobs.kcl.ac.uk/gb/en/job/040205/Research-Associate","fileUrl1":null,"fileUrl2":null,"fileUrl3":null,"fileUrl4":null,"fileUrl5":null,"fileUrl6":null,"fileUrl7":null,"workingHour":"Full Time","contractType":"Fixed Term","salary":"£38,826 per annum, including London Weighting","original_id":"UNI|279496","original_domain":"timeshighereducation.com","original_url":"https://www.timeshighereducation.com/unijobs/listing/279496","original_isPremium":null,"closeType":1,"closedAt":"2022-02-28T00:00:00.000Z","requireEducation":10,"managerTel":null,"managerFax":null,"managerEmail":null,"managerName":"KINGS COLLEGE LONDON","managerPhone":null,"managerAddress":"London (Greater)","log_hit":3,"log_like":0,"publishState":1,"organizationName":null,"organizationName_en":null,"organizationName_alt":null,"del_yn":"N","createdAt":"2022-02-07T20:44:02.000Z","updatedAt":"2022-02-07T20:44:02.000Z"},"organization":{"organizationId":494,"lv1Id":null,"lv2Id":null,"name":"King’s College London","name_en":"KINGS COLLEGE LONDON","name_alt":",King’s College London,KINGS COLLEGE LONDON,","introduction":"<p>King’s is a leading university providing world-class teaching and cutting-edge research. We are ranked sixth in the UK for the quality and quantity of research activity (Research Excellence Framework 2014). King’s has played a major role in many of the advances that shape modern life, such as the discovery of the structure of DNA and research that led to the development of radio, television, mobile phones and radar. King’s continues to lead the way on research and pioneers new ideas to make the world a better place.</p><p> </p><p>King’s is London’s most central university, with five campuses linked through the heart of the capital, enabling us to build partnerships with key London institutions and form international conversations. We collaborate on research projects, share teaching resources and create internship opportunities to enhance our students’ experience. Current partners include the British Library, British Museum, National Gallery, Shakespeare’s Globe, Southbank Centre, Tate Modern, and more. Our central location and varied partnerships allow students to get connected in one of the world’s most dynamic cities.</p><p>King’s is not only an enriching experience from an academic perspective – we have a diverse and active student community, with almost 30,000 students from some 150 countries worldwide.</p>","logoImg":"","logoImgSquare":"https://s3.ap-northeast-2.amazonaws.com/jobs.ac.kr/dev/images/fdoip_897356079989.png","homepageUrl":"https://www.kcl.ac.uk/study","infoUrl":"https://www.timeshighereducation.com/world-university-rankings/kings-college-london","country":"GB","state":"London","location":"유럽","address":"Strand, London, WC2R 2LS, United Kingdom","phoneNumber":"+44 20 7836 5454","faxNumber":"","type":1,"univType1":"대학","univType2":"대학교","univType3":"","univType4":"본교","establishedAt":"1829-01-05T00:00:00.000Z","count_majors":null,"count_students":null,"meta_competitiveness":"","publishState":1,"updatedAt":"2021-03-23T10:36:30.000Z","createdAt":"2020-03-04T20:13:07.000Z","default_1_bannerImage":null,"default_1_bannerImageMobile":null,"default_2_bannerImage":null,"default_2_bannerImageMobile":null,"default_3_bannerImage":"https://s3.ap-northeast-2.amazonaws.com/jobs.ac.kr/production/images/1647409098220/KINGS COLLEGE LONDON.jpg","default_3_bannerImageMobile":null}}