{"job":{"jobId":2423518,"fk_accountId":null,"fk_organizationId":483,"fk_adminAccountId":null,"title":"Research Fellow, Mechanobiology Institute","description":"\n\n<p style=\"margin-bottom: 20px; font-family: san-serif;\"><b>Job Description</b></p>\n\n\n<p style=\"margin-bottom: 20px; font-family: san-serif;\">We are seeking to recruit a Research Fellow (Postdoctoral Fellow) in nanobiotechnology at Mechanobiology Institute, National University of Singapore. The research project aims to elucidate mechanisms of cellular adaptations to aging process and are jointly supervised by Mechanobiology Institute, National University of Singapore (MBI, NUS; PI: Assoc. Prof. Pakorn Kanchanawong) and Nanyang Technology University (NTU, PI: Asst Prof. Zhao Wenting). The research project is devoted to the study of nanoscale membrane reorganization in aging using nanofabrication-enabled cellular manipulation in conjunction with high-resolution live cell imaging, per references below.</p>\n\n\n<ol>\n</ol>\n\n\n<p style=\"margin-bottom: 20px; font-family: san-serif;\">References</p>\n\n\n<ol>\n<li>\"Tutorial: using nanoneedles for intracellular delivery.\" <b> </b>Chiappini, C., Chen Y., Aslanoglou S., Mariano A., Mollo V., Mu H., De Rosa E., He G., Tasciotti E., Xie X., Santoro F., <b> </b>Zhao, W.T., Voelcker N. H. and Elnathan R., <b>Nature Protocols,</b> 2021, 12, 4539-4563..</li>\n<li>\"Comparative Study of Curvature Sensing Mediated by F-BAR and an Intrinsically Disordered Region of FBP17.\" Su, M., Zhuang Y., Miao X., Zeng Y., Gao W., Zhao, W.T. and Wu M. <b>iScience,</b> 2020, <b>23</b>(11): 101712.</li>\n<li>\"Membrane curvature underlies actin reorganization in response to nanoscale surface topography\", Lou, H.Y.; Zhao, W. T.; Li, X.; Duan, L.; Powers, A.; Akamatsu, M.; Santoro, F.; McGuire, A.F.; Cui, Y.; Drubin, D.G.; Cui, B.X., <b>Proceedings of the National Academy of Sciences, U. S. A.</b><b>,</b> 2019, 116 (46), 23143-23151.</li>\n<li>\"A nanostructure platform for live cell manipulation of membrane curvature\", Li, X., Matino L., Zhang, W., Klausen, L., McGuire, A., Lubrano, C., <b>Zhao, W.T., </b>Santoro, F., Cui, B., <b>Nature Protocols,</b> 2019, 14, 1772–1802.</li>\n<li>\"The role of membrane curvature in nanoscale topography-induced intracellular signalling\". Lou, H.Y.; <b>Zhao, W. T.</b>; Zeng, Y., Cui, B. X., <b>Accounts of Chemical Research, </b>2018, 51 (5), 1046–1053.</li>\n<li>\"Nanoscale manipulation of membrane curvature for probing endocytosis in live cells\". Zhao, W. T.; Hanson, L.; Lou, H.Y.; Akamatsu, M.; Chowdary, P.; Santoro, F.; Marks, J.; Grassart, A.; Drubin, D. G., Cui, Y.; Cui, B. X., <b>Nature Nanotechnology</b>, 2017, 12, 750-756.</li>\n<li>\"Vertical nanopillars for in situ probing of nuclear mechanics in adherent cells\". Hanson, L.; Zhao, W. T.; Lou, H.Y.; Lin, Z. L.; Lee, S.W.; Chowdary, P.; Cui, Y.; Cui, B. X., <b>Nature Nanotechnology, </b>2015, 10, (6), 554-562.</li>\n</ol>\n\n\n<p style=\"margin-bottom: 20px; font-family: san-serif;\"><strong>Responsibilities</strong></p>\n\n\n<ul>\n<li>Design, develop, perform, and implement scientific project on nanoscale membrane dynamics in cells.</li>\n<li>Collaborate with other team members, train and supervise junior laboratory members</li>\n<li>Write scientific manuscript and assist with grant proposal preparation.</li>\n</ul>\n\n\n<p style=\"margin-bottom: 20px; font-family: san-serif;\"><b>Qualifications</b></p>\n\n\n<ul>\n<li>A Ph.D in materials science, chemistry, biophysics, biomedical engineering or related disciplines. Background in material surface engineering is highly preferred.</li>\n<li>Recent Ph.D graduates with less than 2 year experience are preferred.</li>\n<li>Strong track record in research accomplishment, such as having high quality first-authored publications.</li>\n<li>Extensive experiences in nanomaterials synthesis, surface patterning, topography engineering, nano-/micro-fabrication and related techniques.</li>\n<li>Experiences in mammalian cell culture, immunofluorescence microscopy, cell transfection, and background knowledge in cell adhesion and gene transcription regulation.</li>\n<li>Experiences in advanced microscopy, high-resolution cell imaging, and computer-based image analysis is desirable.</li>\n</ul>\n\n\n<p style=\"margin-bottom: 20px; font-family: san-serif;\">Please attach your full CV, with the names and contacts (including email addresses) of three references in addition to the Ph.D. supervisor.</p>\n\n\n<p style=\"margin-bottom: 20px; font-family: san-serif;\">We regret that only shortlisted candidates will be notified.</p>\n\n\n<p style=\"margin-bottom: 20px; font-family: san-serif;\"><b>More Information</b></p>\n\n\n<p style=\"margin-bottom: 20px; font-family: san-serif;\"><strong>Location</strong>: Kent Ridge Campus\n<strong>Organization</strong>: Mechanobiology Institute\n<strong>Department </strong>: Research\n<strong>Job requisition ID :</strong> 10293</p>\n\n\n","pdfUrl1":null,"location":"Singapore","location1":"아시아","location2":null,"location3":null,"type":"2","applyUrl":"https://careers.nus.edu.sg/NUS/job/Kent-Ridge-Research-Fellow-%28Mechanobiology-Institute%29-Kent/6410844/","fileUrl1":null,"fileUrl2":null,"fileUrl3":null,"fileUrl4":null,"fileUrl5":null,"fileUrl6":null,"fileUrl7":null,"workingHour":"Full Time","contractType":"Permanent","salary":null,"original_id":"UNI|281188","original_domain":"timeshighereducation.com","original_url":"https://www.timeshighereducation.com/unijobs/listing/281188","original_isPremium":null,"closeType":1,"closedAt":"2022-03-13T00:00:00.000Z","requireEducation":10,"managerTel":null,"managerFax":null,"managerEmail":null,"managerName":"NATIONAL UNIVERSITY OF SINGAPORE","managerPhone":null,"managerAddress":"Singapore","log_hit":7,"log_like":0,"publishState":1,"organizationName":null,"organizationName_en":null,"organizationName_alt":null,"del_yn":"N","createdAt":"2022-02-11T18:50:26.000Z","updatedAt":"2022-02-11T18:50:26.000Z"},"organization":{"organizationId":483,"lv1Id":null,"lv2Id":null,"name":"National University of Singapore","name_en":"National University of Singapore","name_alt":",","introduction":"<p>As Singapore’s flagship university and among Asia’s best, the <a href=\"http://www.nus.edu.sg/\">National University of Singapore (NUS)</a> offers a global approach to education, research and entrepreneurship, with a focus on Asian perspectives and expertise.</p><p> </p><p>Our 17 faculties across three campuses in Singapore – Kent Ridge, Bukit Timah and Outram – provide a rigorous broad-based curriculum underscored by cross-faculty enrichment. We have pioneered many innovative academic programmes which include student exchange, entrepreneurial internships at <a href=\"https://enterprise.nus.edu.sg/educate/nus-overseas-colleges\">12 NUS Overseas Colleges</a>, as well as double, joint and concurrent degree programmes with some of the world’s best universities. Close to 40,000 students from 100 countries enrich our vibrant and diverse campus community.</p><p> </p><p>The University’s multidisciplinary and real-world approach to education, research and entrepreneurship enables us to work closely with industry, governments and academia to address crucial and complex issues relevant to Asia and the world. Researchers in our faculties, 29 university-level research institutes, research centres of excellence and corporate labs focus on themes that include energy, environmental and urban sustainability; treatment and prevention of diseases common among Asians; active ageing; advanced materials; as well as risk management and resilience of financial systems. The University’s latest research focus is to use data science, operations research and cybersecurity to support Singapore's Smart Nation initiative. We also strive to create a supportive and innovative environment to promote creative enterprise within our community.</p>","logoImg":"https://s3.ap-northeast-2.amazonaws.com/jobs.ac.kr/dev/images/다운로드(2)_1347216054377.png","logoImgSquare":"https://s3.ap-northeast-2.amazonaws.com/jobs.ac.kr/dev/bin/1200px-NUS_coat_of_arms_196665413153.svg","homepageUrl":"http://www.nus.edu.sg","infoUrl":"https://www.timeshighereducation.com/world-university-rankings/national-university-singapore","country":"SG","state":"Singapore","location":"아시아","address":"21 Lower Kent Ridge Road, 119077, Singapore","phoneNumber":"+65 6516 6666","faxNumber":"","type":1,"univType1":"대학","univType2":"대학교","univType3":"","univType4":"본교","establishedAt":"1970-01-01T00:00:00.000Z","count_majors":null,"count_students":null,"meta_competitiveness":"","publishState":1,"updatedAt":"2020-04-03T18:01:08.000Z","createdAt":"2020-03-04T20:13:07.000Z","default_1_bannerImage":null,"default_1_bannerImageMobile":null,"default_2_bannerImage":null,"default_2_bannerImageMobile":null,"default_3_bannerImage":"https://s3.ap-northeast-2.amazonaws.com/jobs.ac.kr/production/images/1653632913461/nus.jpg","default_3_bannerImageMobile":null}}