Research Fellow, Pharmacy - JOBS.ac.kr(잡스) - 대한민국 최대 석박사 채용정보, 잡스!

{"job":{"jobId":2423790,"fk_accountId":null,"fk_organizationId":483,"fk_adminAccountId":null,"title":"Research Fellow, Pharmacy","description":"\n\nJob Description\n\n\nThe laboratory of A/Prof Victor Yu at the National University of Singapore (NUS) is currently recruiting (Postdoctoral) Research Fellow. \n\n\nWe are seeking a highly motivated post-doctoral fellow to work on a project aimed at elucidating roles of MOAP-1 in regulating cellular signaling mechanisms associated with senescence, metabolism and inflammation relevant for gaining understanding of the development and progression of chronic liver diseases such as NAFLD, NASH and HCC.\n\n\nTo facilitate a better understanding of the work being pursued in the laboratory, prospective applicants can refer to the following papers published by the lab: \n\n\nK.O. Tan et al., MAP-1 is a mitochondrial effector of Bax, (Track II), Proc. Natl. Acad. Sci. USA, 102: 14623-14688, 2005. (<a data-mz=\"\" href=\"https://doi.org/10.1073/pnas.0503524102\" rel=\"no-follow\" target=\"_blank\">https://doi.org/10.1073/pnas.0503524102</a>)\n\n\nN.Y. Fu et al., Inhibition of ubiquitin-mediated degradation of MOAP-1 by apoptotic stimuli promotes Bax function in mitochondria, (Track II), Proc. Natl. Acad. Sci. USA, 104: 10051-10056, 2007. (<a data-mz=\"\" href=\"https://doi.org/10.1073/pnas.0700007104\" rel=\"no-follow\" target=\"_blank\">https://doi.org/10.1073/pnas.0700007104</a>)\n\n\nN.Y. Fu et al., Baxbeta: a constitutively active human Bax isoform that is under tight regulatory control by the proteasomal degradation mechanism, Molecular Cell, 33: 15-29, 2009. (<a data-mz=\"\" href=\"https://doi.org/10.1016/j.molcel.2008.11.025\" rel=\"no-follow\" target=\"_blank\">https://doi.org/10.1016/j.molcel.2008.11.025</a>)\n\n\nS.K. Sukumaran et al., A soluble form of the pilus protein FimA targets the VDAC-hexokinase complex at mitochondria to inhibit host cell apoptosis, Molecular Cell, 37: 768-783, 2010. (<a data-mz=\"\" href=\"https://doi.org/10.1016/j.molcel.2010.02.015\" rel=\"no-follow\" target=\"_blank\">https://doi.org/10.1016/j.molcel.2010.02.015</a>)\n\n\nC.T. Tan et al., MOAP-1 Mediates Fas-Induced Apoptosis in Liver by Facilitating tBid Recruitment to Mitochondria, Cell Reports, 16:174-85, 2016.  (<a data-mz=\"\" href=\"https://doi.org/10.1016/j.celrep.2016.05.068\" rel=\"no-follow\" target=\"_blank\">https://doi.org/10.1016/j.celrep.2016.05.068</a>)\n\n\nC.T. Tan et al., MOAP-1-mediated dissociation of p62/SQSTM1 bodies releases Keap1 and suppresses Nrf2 signaling, EMBO Reports, 22: e50854, 2021. (Featured as the cover story in Jan, 2021 issue: <a data-mz=\"\" href=\"https://doi.org/10.15252/embr.202050854\" rel=\"no-follow\" target=\"_blank\">https://doi.org/10.15252/embr.202050854</a>) \n\n\nH.C. Chang et al., The BAX-binding protein MOAP1 associates with LC3 and promotes closure of the phagophore, Autophagy, 2021. (<a data-mz=\"\" href=\"https://doi.org/10.1080/15548627.2021.1896157\" rel=\"no-follow\" target=\"_blank\">https://doi.org/10.1080/15548627.2021.1896157</a>)\n\n\nResponsibilities:\n\n\n<ul>\n<li>Planning and execution of experiments </li>\n<li>Guiding and Working with junior staffs including students</li>\n<li>Participation in preparation of manuscripts</li>\n<li>Upholding research integrity and ensuring safety compliance </li>\n</ul>\n\n\nInterested candidates please submit full curriculum vitae and contact information for 3 references to A/Prof Victor Yu at <a data-mz=\"\" href=\"mailto:phayuv@nus.edu.sg\" rel=\"no-follow\">phayuv@nus.edu.sg</a>. Please note that only shortlisted candidates will be notified.\n\n\nQualifications\n\n\nQualifications / Discipline:\n\n\n<ul>\n<li>PhD degree in Molecular Biology, Biochemistry, Cancer biology or other related fields is preferred.</li>\n</ul>\n\n\nExperience:  \n\n\n<ul>\n<li>Applicants with research experiences in mouse models and/or molecular and cell biology techniques (e.g., primary cell preparations, CRISPR-Cas9 gene editing, confocal microscopy, FACS, histology, IHC, IF or protein-protein interaction) are preferred.</li>\n</ul>\n\n\nMore Information\n\n\nLocation: Kent Ridge Campus\nOrganization: Science\nDepartment : Pharmacy\nJob requisition ID : 8417\n\n\n","pdfUrl1":null,"location":"Singapore","location1":"아시아","location2":null,"location3":null,"type":"2","applyUrl":"https://careers.nus.edu.sg/NUS/job/Kent-Ridge-Research-Fellow-%28Pharmacy%29-Kent/5773844/","fileUrl1":null,"fileUrl2":null,"fileUrl3":null,"fileUrl4":null,"fileUrl5":null,"fileUrl6":null,"fileUrl7":null,"workingHour":"Full Time","contractType":"Permanent","salary":null,"original_id":"UNI|281561","original_domain":"timeshighereducation.com","original_url":"https://www.timeshighereducation.com/unijobs/listing/281561","original_isPremium":null,"closeType":1,"closedAt":"2022-03-17T00:00:00.000Z","requireEducation":10,"managerTel":null,"managerFax":null,"managerEmail":"phayuv@nus.edu.sg","managerName":"NATIONAL UNIVERSITY OF SINGAPORE","managerPhone":null,"managerAddress":"Singapore","log_hit":4,"log_like":0,"publishState":1,"organizationName":null,"organizationName_en":null,"organizationName_alt":null,"del_yn":"N","createdAt":"2022-02-16T19:24:03.000Z","updatedAt":"2022-02-16T19:24:03.000Z"},"organization":{"organizationId":483,"lv1Id":null,"lv2Id":null,"name":"National University of Singapore","name_en":"National University of Singapore","name_alt":",","introduction":"As Singapore’s flagship university and among Asia’s best, the <a href=\"http://www.nus.edu.sg/\">National University of Singapore (NUS)</a> offers a global approach to education, research and entrepreneurship, with a focus on Asian perspectives and expertise.&nbsp;Our 17 faculties across three campuses in Singapore – Kent Ridge, Bukit Timah and Outram – provide a rigorous broad-based curriculum underscored by cross-faculty enrichment. We have pioneered many innovative academic programmes which include student exchange, entrepreneurial internships at <a href=\"https://enterprise.nus.edu.sg/educate/nus-overseas-colleges\">12 NUS Overseas Colleges</a>, as well as double, joint and concurrent degree programmes with some of the world’s best universities. Close to 40,000 students from 100 countries enrich our vibrant and diverse campus community.&nbsp;The University’s multidisciplinary and real-world approach to education, research and entrepreneurship enables us to work closely with industry, governments and academia to address crucial and complex issues relevant to Asia and the world. Researchers in our faculties, 29 university-level research institutes, research centres of excellence and corporate labs focus on themes that include energy, environmental and urban sustainability; treatment and prevention of diseases common among Asians; active ageing; advanced materials; as well as risk management and resilience of financial systems. The University’s latest research focus is to use data science, operations research and cybersecurity to support Singapore's Smart Nation initiative. We also strive to create a supportive and innovative environment to promote creative enterprise within our community.","logoImg":"https://s3.ap-northeast-2.amazonaws.com/jobs.ac.kr/dev/images/다운로드(2)_1347216054377.png","logoImgSquare":"https://s3.ap-northeast-2.amazonaws.com/jobs.ac.kr/dev/bin/1200px-NUS_coat_of_arms_196665413153.svg","homepageUrl":"http://www.nus.edu.sg","infoUrl":"https://www.timeshighereducation.com/world-university-rankings/national-university-singapore","country":"SG","state":"Singapore","location":"아시아","address":"21 Lower Kent Ridge Road, 119077, Singapore","phoneNumber":"+65 6516 6666","faxNumber":"","type":1,"univType1":"대학","univType2":"대학교","univType3":"","univType4":"본교","establishedAt":"1970-01-01T00:00:00.000Z","count_majors":null,"count_students":null,"meta_competitiveness":"","publishState":1,"updatedAt":"2020-04-03T18:01:08.000Z","createdAt":"2020-03-04T20:13:07.000Z","default_1_bannerImage":null,"default_1_bannerImageMobile":null,"default_2_bannerImage":null,"default_2_bannerImageMobile":null,"default_3_bannerImage":"https://s3.ap-northeast-2.amazonaws.com/jobs.ac.kr/production/images/1653632913461/nus.jpg","default_3_bannerImageMobile":null}}