Postdoctoral Fellow, Targeting of Pathogens - JOBS.ac.kr(잡스) - 대한민국 최대 석박사 채용정보, 잡스!

{"job":{"jobId":2496197,"fk_accountId":null,"fk_organizationId":1158,"fk_adminAccountId":null,"title":"Postdoctoral Fellow, Targeting of Pathogens","description":"\n\nDepartment: <a data-mz=\"\" href=\"https://www.muni.cz/en/about-us/organizational-structure/ceitec/711020-robert-vacha-rg\" rel=\"no-follow\" target=\"_blank\">Robert Vácha Research Group </a>– <a data-mz=\"\" href=\"https://www.muni.cz/en/about-us/organizational-structure/ceitec\" rel=\"no-follow\" target=\"_blank\">Central European Institute of Technology</a>\nDeadline: 1 Dec 2023\nStart date: negotiable\nJob type: full-time\nJob field: Science and research\n\n\nCentral European Institute of Technology of Masaryk University (CEITEC MU) \n\n\nBrno, Czech Republic | <a data-mz=\"\" href=\"http://www.ceitec.eu/\" rel=\"no-follow\" target=\"_blank\">www.ceitec.eu</a>\n\n\nWe are the Czech Republic’s flagship basic research institute based at Masaryk University. Our modern in-house core facilities, which provide open access to the latest technologies and expertise, currently support more than 500 researchers from over 35 countries, who are together pushing the boundaries of knowledge in the areas of structural biology, molecular medicine, genomics and proteomics of plant systems, and neuroscience.\n\n\nOur <a data-mz=\"\" href=\"https://www.ceitec.eu/postdoctoral-programme/t9984\" rel=\"no-follow\" target=\"_blank\">postdoctoral programme</a> will enable you to participate in one of many exciting scientific projects addressing current global issues related to health and the quality of human life. You will have the opportunity to discuss and develop ideas and train your ability to reason in a scientific manner, formulate hypotheses independently, to innovate, and to perform independent research. It is an excellent opportunity to fully develop the skills acquired throughout your PhD studies. You will have access to a professional administration supporting you with grant preparation and administration, with technology transfer, science communication and with other areas of modern research management. You will have the chance to participate in a wide range of scientific and career development events and become a valued member of our vibrant multinational scientific community.\n\n\nAbout this position \n\n\nAntimicrobial peptides (AMPs) possess the ability to disrupt the membrane barrier function, effectively eliminating bacteria, viruses, and even cancer cells. Consequently, AMPs have emerged as promising candidates for the development of a new class of therapeutics. However, the majority of known AMPs exhibit toxic properties due to their origin from human-unfriendly sources, such as venoms. Our understanding of peptide targeting mechanisms towards specific pathogens and their membranes remains limited, hindering further peptide development. This ERC funded project aims to identify peptide sequence motifs that are responsible for selective targeting pathogens with respect to human cells. Apart from the differences in lipid composition of membranes, we will investigate the impact of membrane local curvature. The main tool for the study will be Molecular dynamics simulations with free energy calculations using Gromacs program package. These simulations will be complemented by in-house experiments providing crucial verification and feedback on peptide-membrane affinity. The acquired knowledge will guide the design of de novo peptides with enhanced pathogen-targeting specificity.\n\n\nThis ERC funded project aims to identify peptide sequence motifs that are responsible for targeting pathogens, while maintaining minimal toxicity towards human cells. In conjunction with the lipid composition of membranes, we will investigate the impact of membrane local curvature. The main tool will be Molecular dynamics simulations with free energy calculations using Gromacs program package. These simulations will be complemented by in-house experiments providing crucial verification and feedback on peptide-membrane affinity. The acquired knowledge will guide the design of de novo peptides with enhanced pathogen-targeting specificity.\n\n\nYou have (necessary competencies) \n\n\n<ul>\n<li>PhD in computational simulations and related fields</li>\n<li>Theoretical knowledge of Molecular Dynamics and free energy calculations</li>\n<li>Some years of work experience in simulations with proteins/membranes and their analysis</li>\n<li>Published in impactful journals in the field, corresponding to given stage of career demonstrating creativity and scientific quality</li>\n<li>Good English language – spoken and written</li>\n<li>Motivated person with collaborative mind set</li>\n</ul>\n\n\nWhy join us?  \n\n\nWe value our employees, and we support them from their very first day at CEITEC. We are an inclusive, equal opportunity employer and offer a highly collaborative, collegial and family friendly, international working environment with relocation assistance through our Welcome Office. The selected candidate will become a valued member of the CEITEC scientific community with access to in-house core facilities and professional administrative support. <a data-mz=\"\" href=\"https://www.ceitec.eu/why-work-at-ceitec/t10425\" rel=\"no-follow\" target=\"_blank\">Have a look at what your potential peers say about working at CEITEC MU.</a>\n\n\n<a data-mz=\"\" href=\"https://www.ceitec.eu/life-in-brno/t10426\" rel=\"no-follow\" target=\"_blank\">Brno</a> is a lively city surrounded by beautiful countryside. It is a top destination for many educated expatriates working in the areas of science and technology. Brno is located in the heart of Europe and offers a great standard of living.\n\n\nWe are offering:\n\n\n<ul>\n<li>Team environment of excellent scientists</li>\n<li>In house core facilities</li>\n<li>Background of a recognized and successful institution with supportive and international working environment</li>\n<li>Environment promoting interdisciplinarity research</li>\n<li>Support of administrative departments (including grant office service)</li>\n<li>Support with the relocation process (welcome office service)</li>\n<li>An attractive salary and benefits package</li>\n<li>6 weeks of paid holiday</li>\n</ul>\n\n\nAnticipated start date: Negotiable\n\n\nCEITEC MU is a proud holder of the European Commission’s <a data-mz=\"\" href=\"http://muni.ceitec.cz/en/hr-strategy-hrs4r/\" rel=\"no-follow\" target=\"_blank\">HR Excellence in Research Award</a>. \n\n\nWhat else you need to know \n\n\nApplication including CV, a brief motivation letter and contacts for referees should be sent by e-application.\n\n\nIn case of any questions about job offer, please contact: Robert Vácha (<a data-mz=\"\" href=\"mailto:kostas.tripsianes@ceitec.muni.cz\" rel=\"no-follow\">robert.vacha@ceitec.muni.cz</a>).\n\n\nIn case of any troubles with filling the e-application, please contact: Petra Obšelová (<a data-mz=\"\" href=\"http://petra.obselova@ceitec.muni.cz/\" rel=\"no-follow\">petra.obselova@ceitec.muni.cz</a>).\n\n\nElectronic application deadline is 1 December 2023. \n\n\nCandidates will be invited for interviews on an ongoing basis.\n\n\nSelection procedure committee members are: the head of the research group and a representative of the HR department.\n\n\nFor more information about the recruitment process, refer to <a data-mz=\"\" href=\"https://is.muni.cz/do/ceitec/uredni_deska/politiky_a_koncepce/CEITEC-MU_Recruitment_Policy_Final_2020-11-24_Approved.pdf\" rel=\"no-follow\" target=\"_blank\">CEITEC MU Recruitment Policy</a>.  \n\n\nFor more information about our career system, refer to <a data-mz=\"\" href=\"https://is.muni.cz/do/ceitec/uredni_deska/opatreni_reditele/opatreni_reditele_2018_09_-_karierni_system/Directors_Measure_CEITEC_MU_09-2018_Career_System_As_Amended_Effective_2020-01-01.pdf\" rel=\"no-follow\" target=\"_blank\">CEITEC MU Career System</a>.\n\n\nIn justified cases, the job announcer can extend, interrupt or cancel the selection procedure. \n\n\n","pdfUrl1":null,"location":"Brno, Czech Republic","location1":"유럽","location2":null,"location3":null,"type":"2","applyUrl":"https://www.muni.cz/en/about-us/careers/vacancies/76775","fileUrl1":null,"fileUrl2":null,"fileUrl3":null,"fileUrl4":null,"fileUrl5":null,"fileUrl6":null,"fileUrl7":null,"workingHour":"Full Time","contractType":"Permanent","salary":null,"original_id":"UNI|355690","original_domain":"timeshighereducation.com","original_url":"https://www.timeshighereducation.com/unijobs/listing/355690","original_isPremium":null,"closeType":1,"closedAt":"2023-12-01T00:00:00.000Z","requireEducation":10,"managerTel":"","managerFax":null,"managerEmail":"petra.obselova@ceitec.muni.cz","managerName":"MASARYK UNIVERSITY","managerPhone":null,"managerAddress":"Brno, Czech Republic","log_hit":4,"log_like":0,"publishState":1,"organizationName":null,"organizationName_en":null,"organizationName_alt":null,"del_yn":"N","createdAt":"2023-10-22T17:30:25.000Z","updatedAt":"2023-10-22T17:30:25.000Z"},"organization":{"organizationId":1158,"lv1Id":null,"lv2Id":null,"name":"Masaryk University","name_en":"Masaryk University","name_alt":",Masaryk University,","introduction":"Founded in 1919 and named after the country’s first president - Tomáš Masaryk - Masaryk University was born just a year after the state of Czechoslovakia itself. It still embodies the republican and democratic spirit of the times in its commitment to remaining autonomous and giving students an important role in designing their own courses. Close to 200,000 students have now passed through its doors.&nbsp;Based in Brno, Masaryk University has a staff of over 5,000 (more than 2,000 of them academics), which makes it the leading employer in South Moravia and the leading public university in the whole of Moravia as well as the second largest in the Czech Republic. One of the fastest-expanding universities in Europe, it is also able to be highly selective, since places to study there are the most sought after in the country. The total student body, scattered across over 200 different departments, institutes and clinics, is more than 40,000, over 7,000 of them from overseas.&nbsp;A leading research institution, Masaryk University offers courses across the full spectrum of traditional and contemporary fields, but with a particular focus on science. In 2006, for example, it set up a pioneering university research station in the Antarctic to explore the parts of the terrain which are ice-free. Four years later, with the help of around 200 million Euros in financial support from the European Union, it completed the construction of a new campus at Bohunice, Further developments have seen the overall area it covers rise to 70,000 square metres. It is now home to a range of facilities, including the Central European Research Centre of Excellence, equipped with state-of-the-art laboratories in life science and advanced materials, and the Centre for Toxic Compounds in the Environment.","logoImg":"","logoImgSquare":"https://s3.ap-northeast-2.amazonaws.com/jobs.ac.kr/dev/images/dsjlfkjxclkjv_409206260272.png","homepageUrl":"http://www.muni.cz/","infoUrl":"https://www.timeshighereducation.com/world-university-rankings/masaryk-university","country":"CZ","state":"Brno","location":"유럽","address":"Žerotínovo námestí 9 Rektorát, Brno-mesto, Brno, Czech Republic","phoneNumber":"+420 549 491 111","faxNumber":"","type":1,"univType1":"대학","univType2":"대학교","univType3":"","univType4":"본교","establishedAt":"1919-01-28T00:00:00.000Z","count_majors":null,"count_students":null,"meta_competitiveness":"","publishState":1,"updatedAt":"2020-03-18T14:33:59.000Z","createdAt":"2020-03-04T20:13:07.000Z","default_1_bannerImage":null,"default_1_bannerImageMobile":null,"default_2_bannerImage":null,"default_2_bannerImageMobile":null,"default_3_bannerImage":null,"default_3_bannerImageMobile":null}}