Research Assistant (Chemistry) - JOBS.ac.kr(잡스) - 대한민국 최대 석박사 채용정보, 잡스!

{"job":{"jobId":2496799,"fk_accountId":null,"fk_organizationId":483,"fk_adminAccountId":null,"title":"Research Assistant (Chemistry)","description":"\n\nJob Description\n\n\nNon-viral transfection agents are essential components in RNA-based therapeutics and diagnostics. Consider for example that the recently developed vaccines for preventing COVID-19 caused by SARS-CoV-2 rely on lipid nanoparticle (LNP) formulations that stabilize mRNA and promote its desired immune response. While LNPs have been largely successful in the control of the COVID-19 pandemic, there are still many issues to improve on including off-target effects, stability, and toxicity. Conjugated oligoelectrolytes (COE) are defined by a linear hydrophobic conjugated backbone with polar ionic pendants at both terminals. The modular design of COEs allows for rapid tuning of molecular units to access a large continuum of properties. They were first synthesized in Prof. Bazan’s group as two-photo absorption chromophores and later extended to several biological applications such as antimicrobial agents and extracellular vesicle dyes.  \nIn this project, we are interested in developing novel LNP formulations incorporating COEs with a view toward theranostic applications in vaccine development. Routine assays will be conducted on the LNP, including particle characterizations (DLS, cryo-TEM, and encapsulation efficiency), transfection, cellular uptake, and confocal imaging of intracellular fates. The performance of the novel LNP formulations will be routinely compared to commercial agents. The photophysical characterizations for these COE-LNP formulations will also be investigated via different spectroscopy-based techniques such as UV-Vis absorbance and fluorescence. \nThis project will be closely mentored by a postdoctoral research fellow and principal investigator, Prof Bazan. \n\n\nQualifications\n\n\n<ul>\n<li>Bachelor’s degree in chemistry or related discipline.</li>\n<li>Independent and motivated individual with good problem-solving skills.</li>\n<li>With practical experience and/or knowledge of \n\t<ul>\n<li>Biological chemistry, cell biology, or biochemistry.</li>\n<li>Biomaterials/materials science. </li>\n<li>Characterization techniques including absorbance/fluorescence measurements, flow cytometry, or confocal microscopy.</li>\n<li>Mammalian cell culture techniques.</li>\n<li>Knowledge of lipid nanoparticles and drug/gene delivery is highly sought after.</li>\n<li>MS office.</li>\n</ul>\n</li>\n</ul>\n\n\nMore Information\n\n\nLocation: Kent Ridge Campus\nOrganization: Science\nDepartment: Chemistry\nJob requisition ID: 22495\n\n\n","pdfUrl1":null,"location":"Singapore","location1":"아시아","location2":null,"location3":null,"type":"2","applyUrl":"https://careers.nus.edu.sg/NUS/job/SCIENCE-Research-Assistant-%28Chemistry%29-Kent/19634644/","fileUrl1":null,"fileUrl2":null,"fileUrl3":null,"fileUrl4":null,"fileUrl5":null,"fileUrl6":null,"fileUrl7":null,"workingHour":"Full Time","contractType":"Fixed Term","salary":null,"original_id":"UNI|355876","original_domain":"timeshighereducation.com","original_url":"https://www.timeshighereducation.com/unijobs/listing/355876","original_isPremium":null,"closeType":1,"closedAt":"2023-11-22T00:00:00.000Z","requireEducation":10,"managerTel":null,"managerFax":null,"managerEmail":null,"managerName":"NATIONAL UNIVERSITY OF SINGAPORE","managerPhone":null,"managerAddress":"Singapore","log_hit":2,"log_like":0,"publishState":1,"organizationName":null,"organizationName_en":null,"organizationName_alt":null,"del_yn":"N","createdAt":"2023-10-23T15:11:00.000Z","updatedAt":"2023-10-23T15:11:00.000Z"},"organization":{"organizationId":483,"lv1Id":null,"lv2Id":null,"name":"National University of Singapore","name_en":"National University of Singapore","name_alt":",","introduction":"As Singapore’s flagship university and among Asia’s best, the <a href=\"http://www.nus.edu.sg/\">National University of Singapore (NUS)</a> offers a global approach to education, research and entrepreneurship, with a focus on Asian perspectives and expertise.&nbsp;Our 17 faculties across three campuses in Singapore – Kent Ridge, Bukit Timah and Outram – provide a rigorous broad-based curriculum underscored by cross-faculty enrichment. We have pioneered many innovative academic programmes which include student exchange, entrepreneurial internships at <a href=\"https://enterprise.nus.edu.sg/educate/nus-overseas-colleges\">12 NUS Overseas Colleges</a>, as well as double, joint and concurrent degree programmes with some of the world’s best universities. Close to 40,000 students from 100 countries enrich our vibrant and diverse campus community.&nbsp;The University’s multidisciplinary and real-world approach to education, research and entrepreneurship enables us to work closely with industry, governments and academia to address crucial and complex issues relevant to Asia and the world. Researchers in our faculties, 29 university-level research institutes, research centres of excellence and corporate labs focus on themes that include energy, environmental and urban sustainability; treatment and prevention of diseases common among Asians; active ageing; advanced materials; as well as risk management and resilience of financial systems. The University’s latest research focus is to use data science, operations research and cybersecurity to support Singapore's Smart Nation initiative. We also strive to create a supportive and innovative environment to promote creative enterprise within our community.","logoImg":"https://s3.ap-northeast-2.amazonaws.com/jobs.ac.kr/dev/images/다운로드(2)_1347216054377.png","logoImgSquare":"https://s3.ap-northeast-2.amazonaws.com/jobs.ac.kr/dev/bin/1200px-NUS_coat_of_arms_196665413153.svg","homepageUrl":"http://www.nus.edu.sg","infoUrl":"https://www.timeshighereducation.com/world-university-rankings/national-university-singapore","country":"SG","state":"Singapore","location":"아시아","address":"21 Lower Kent Ridge Road, 119077, Singapore","phoneNumber":"+65 6516 6666","faxNumber":"","type":1,"univType1":"대학","univType2":"대학교","univType3":"","univType4":"본교","establishedAt":"1970-01-01T00:00:00.000Z","count_majors":null,"count_students":null,"meta_competitiveness":"","publishState":1,"updatedAt":"2020-04-03T18:01:08.000Z","createdAt":"2020-03-04T20:13:07.000Z","default_1_bannerImage":null,"default_1_bannerImageMobile":null,"default_2_bannerImage":null,"default_2_bannerImageMobile":null,"default_3_bannerImage":"https://s3.ap-northeast-2.amazonaws.com/jobs.ac.kr/production/images/1673600957724/National University of Singapore.jpg","default_3_bannerImageMobile":"https://s3.ap-northeast-2.amazonaws.com/jobs.ac.kr/production/images/1673600962037/National University of Singapore.jpg"}}