Research Assistant x 2 (Gene Therapy) - JOBS.ac.kr(잡스) - 대한민국 최대 석박사 채용정보, 잡스!

{"job":{"jobId":2497613,"fk_accountId":null,"fk_organizationId":494,"fk_adminAccountId":null,"title":"Research Assistant x 2 (Gene Therapy)","description":"\n\nJob description\n\n\nProfessor Chris Shaw is seeking to appoint two Gene Therapy Animal Research Assistants.\n\n\nThe successful candidates will be part of a team testing viral vector gene therapy reagents aimed at treating amyotrophic lateral sclerosis (ALS) and fronto-temporal dementia (FTD) on a commercially funded project. The aim of the project is to optimise the dose and delivery of gene supplement and knock-down vectors in cellular and animal models of disease as proof of concept and efficacy for potential clinical application. Working with Professor Shaw the candidates will join a team of technicians and post-doctoral scientists analysing cells and tissues transduced with plasmid and vector constructs and quantify the effects on target gene expression.  \n\n\nFor in vivo work the candidate will take care of different mouse colonies from breeding to sacrifice stage (including behavioural phenotyping studies), harvest and prepare tissues for histological sectioning, staining, imaging and quantitative analyses. In vivo work will be conducted over two different sites (Denmark Hill and Waterloo Campus). All experiments will be undertaken at a very high standard and all data treated with complete confidentiality. \n\n\nSalary will be determined and agreed based on the evidence of experience the candidates provide as part of the application and interview process. \n\n\nThe candidates will join a research group based within the UK Dementia Research Institute (DRI) centre that is embedded within the Department of Basic and Clinical Neuroscience at King’s College London (<a data-mz=\"\" href=\"https://www.kcl.ac.uk/jobs/www.kcl.ac.uk/ioppn/depts/bcn/dri/lab-groups\" rel=\"no-follow\">www.kcl.ac.uk/ioppn/depts/bcn/dri/lab-groups</a>) within the Maurice Wohl Clinical Neuroscience Institute on the Denmark Hill campus. The DRI is a national consortium focused on cutting-edge dementia research funded by the Medical Research Council, Alzheimer’s Society and Alzheimer’s Research UK (<a data-mz=\"\" href=\"https://www.kcl.ac.uk/jobs/www.ukdri.co.uk\" rel=\"no-follow\">www.ukdri.co.uk</a>)\n\n\nBoth positions will be offered on full-time, fixed term contracts until 31st December 2024.\n\n\nKey responsibilities\n\n\n<ul>\n<li>Perform laboratory work to optimise the efficiency of our preclinical studies.  </li>\n<li>Deliver high-quality data from our preclinical studies including:  </li>\n<li>Undertake rodent colony care (daily monitoring of pups, juvenile and adults), breeding and genotyping, performing licensed procedure as appropriate, </li>\n<li>Undertake rodent behavioural studies (mainly motor deficit phenotyping) </li>\n<li>Optimise perfusion, harvesting, fixation and sectioning of animal tissues, </li>\n<li>Image tissues using slide scanning and confocal microscopes, </li>\n<li>Undertake image analysis using advanced analytical software tools. </li>\n<li>Availability and willingness to work some Weekends and Bank Holidays. </li>\n</ul>\n\n\nThe above list of responsibilities may not be exhaustive, and the post holder will be required to undertake such tasks and responsibilities as may reasonably be expected within the scope and grading of the post.  \n\n\nSkills, knowledge, and experience\n\n\nEssential criteria  \n\n\n1.       BSc and/or MSc in Neuroscience or equivalent biological field \n\n\n2.       Hold or Obtain a Home Office Personal Animal License \n\n\n3.       Experience in genotyping or in rodent colony maintenance  \n\n\n4.       Expertise in animal tissue processing and immunohistochemistry \n\n\n5.       Experience in microscopy \n\n\n6.       Ability to work independently and within a team \n\n\n7.       Administrative skills for careful record keeping  \n\n\n8.       Conscientious and organised \n\n\n9.       Ability to time manage appropriately  \n\n\n10.    Willing to work during some weekends and bank holidays \n\n\nDesirable criteria\n\n\n1.       Knowledge of adeno associated viral (AAV) vector gene therapy \n\n\n2.       Experience of handling viral gene vectors \n\n\n3.       Experience in animal behaviour phenotyping (rotarod, grip test, open-field) \n\n\nFurther information\n\n\n This post is subject to an Occupational Health clearance.\n\n\n","pdfUrl1":null,"location":"London (Greater) (GB)","location1":"유럽","location2":null,"location3":null,"type":"2","applyUrl":"https://www.kcl.ac.uk/jobs/077386-research-assistant-x-2-gene-therapy","fileUrl1":null,"fileUrl2":null,"fileUrl3":null,"fileUrl4":null,"fileUrl5":null,"fileUrl6":null,"fileUrl7":null,"workingHour":"Full Time","contractType":"Fixed Term","salary":"£36,532 - £41,299 per annum, including London","original_id":"UNI|356141","original_domain":"timeshighereducation.com","original_url":"https://www.timeshighereducation.com/unijobs/listing/356141","original_isPremium":null,"closeType":1,"closedAt":"2023-11-22T00:00:00.000Z","requireEducation":10,"managerTel":"","managerFax":null,"managerEmail":null,"managerName":"KINGS COLLEGE LONDON","managerPhone":null,"managerAddress":"London (Greater) (GB)","log_hit":0,"log_like":0,"publishState":1,"organizationName":null,"organizationName_en":null,"organizationName_alt":null,"del_yn":"N","createdAt":"2023-10-26T12:34:29.000Z","updatedAt":"2023-10-26T12:34:29.000Z"},"organization":{"organizationId":494,"lv1Id":null,"lv2Id":null,"name":"King’s College London","name_en":"KINGS COLLEGE LONDON","name_alt":",King’s College London,KINGS COLLEGE LONDON,","introduction":"King’s is a leading university providing world-class teaching and cutting-edge research. We are ranked sixth in the UK for the quality and quantity of research activity (Research Excellence Framework 2014). King’s has played a major role in many of the advances that shape modern life, such as the discovery of the structure of DNA and research that led to the development of radio, television, mobile phones and radar. King’s continues to lead the way on research and pioneers new ideas to make the world a better place.&nbsp;King’s is London’s most central university, with five campuses linked through the heart of the capital, enabling us to build partnerships with key London institutions and form international conversations. We collaborate on research projects, share teaching resources and create internship opportunities to enhance our students’ experience. Current partners include the British Library, British Museum, National Gallery, Shakespeare’s Globe, Southbank Centre, Tate Modern, and more. Our central location and varied partnerships allow students to get connected in one of the world’s most dynamic cities.King’s is not only an enriching experience from an academic perspective – we have a diverse and active student community, with almost 30,000 students from some 150 countries worldwide.","logoImg":"","logoImgSquare":"https://s3.ap-northeast-2.amazonaws.com/jobs.ac.kr/dev/images/fdoip_897356079989.png","homepageUrl":"https://www.kcl.ac.uk/study","infoUrl":"https://www.timeshighereducation.com/world-university-rankings/kings-college-london","country":"GB","state":"London","location":"유럽","address":"Strand, London, WC2R 2LS, United Kingdom","phoneNumber":"+44 20 7836 5454","faxNumber":"","type":1,"univType1":"대학","univType2":"대학교","univType3":"","univType4":"본교","establishedAt":"1829-01-05T00:00:00.000Z","count_majors":null,"count_students":null,"meta_competitiveness":"","publishState":1,"updatedAt":"2021-03-23T10:36:30.000Z","createdAt":"2020-03-04T20:13:07.000Z","default_1_bannerImage":null,"default_1_bannerImageMobile":null,"default_2_bannerImage":null,"default_2_bannerImageMobile":null,"default_3_bannerImage":"https://s3.ap-northeast-2.amazonaws.com/jobs.ac.kr/production/images/1720407274537/Mask group.png","default_3_bannerImageMobile":"https://s3.ap-northeast-2.amazonaws.com/jobs.ac.kr/production/images/1720407278545/Mask group.png"}}